Carbamazepine-induced thrombocytopenia defined by a challenge test

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Carbamazepine (Tegretol)-induced thrombocytopenia.

A case of carbamazepine-induced thrombocytopenia is reported. The patient, a 38-year-old female, developed thrombocytopenia 10 days after receiving 400 mg carbamazepine daily. The presence of an anti-IgG carbamazepine-dependent platelet-reactive antibody was documented. Using flow cytometry, the drug-induced antibody was detected at a drug concentration as low as 10(-6) M.

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 1999

ISSN: 0361-8609,1096-8652

DOI: 10.1002/(sici)1096-8652(199909)62:1<52::aid-ajh9>3.0.co;2-e